Urine Specimen SCOP Rapid Test Dipstick Easy Operation

SCOP Rapid Test Dipstick, Urine Specimen, Scopolamine Rapid Test For Drugs Of Abuset , Easy Operation

SCOP Rapid Test Panel (Urine), Scopolamine Rapid Test For Drugs of Abuset , High accuracy

The SCOP Rapid Test is a rapid chromatographic immunoassay for the detection of Scopol-amine in human urine at a cut-off concentration of 500ng/ ml.

Application 

Scopolamine(SCOP), also known as hyoscine, or Devil's Breath, is a natural or synthetically produced tropane alkaloid and anticholinergic drug that is formallv used as a medication for treating motion sickness and postoperative nausea and vomiting. It may also be used orally and as a transdermal patch.

A travel advisory published by the Overseas Security Advisory Council (OSAC) in 2012 stated;One common and particularly dangerous method that criminals use in order to rob a victim is through the use of drugs, The most common lin Colombial has been scopolamine,Scopo-amine can render a victim unconscious for 24 hours or more. In large doses, it can cause respi-ratory failure and death.

INTENDED USE

The SCOP Rapid Test Panel (Urine) is a rapid chromatographic immunoassay for the detection of Scopolamine in human urine at a cut-off concentration of 500ng/ml. This test will detect other related compounds, please refer to the Analytical Specificity table in this package insert.

This assay provides only a qualitative, preliminary analytical test result. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrometry (GC/MS) is the preferred confirmatory method. Clinicalconsideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are used.

SUMMARY 

Scopolamine is a tertiary amine antifungal drug often used in sedative anesthesia, cough and asthma. It is a muscarinic acetylcholine receptor antagonist that has traditionally been used to treat motion sickness in humans.1,2 It is mainly derived from the Solanaceae plants Tianxian,
mandola and so on. The drug has highly toxic and hallucinogenic effects and is used as a crime, even called the devil's breath.3 Therapeutically,

Scopolamine is used as a substitution treatment for Patients allergic to atropine. In alternative therapy, Scopolamine is as effective as atropine, and even more potent. The plasma half-life of Scopolamine is 1-3 hours.

The SCOP Rapid Test Dipstick (Urine) is a rapid urine screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of Scopolamine in urine. The SCOP Rapid Test Dipstick (Urine) yields a positive result when Scopolamine in urine exceeds 500ng/ml.

PRINCIPLE

The SCOP Rapid Test Dipstick (Urine) is an immunoassay based on the principle of competitive binding. Drugs which may be present in the urine specimen compete against the drug conjugate for binding sites on the antibody. During testing, a urine specimen migrates upward by capillary action. Scopolamine, if present in the urine specimen below the cut-off level, will not saturate the binding sites of the antibody in the test. The antibody coated particles will then be captured by immobilized Scopolamine-protein conjugate and a visible colored line will show up in the test line region. The colored line will not form in the test line region if the Scopolamine level exceeds the cut-off level, because it will saturate all the binding sites of anti-scopolamine antibody.

A drug-positive urine specimen will not generate a colored line in the test line region because of drug competition, while a drug-negative urine specimen or a specimen containing a drug concentration less than the cut-off will generate a line in the test line region. To serve as a procedural control, a colored line will always appear at the control line region indicating that proper volume of specimen has been added and membrane wicking has occurred.

DIRECTIONS FOR USE

Allow the test, urine specimen, and/or controls to reach room temperature (15-30 ℃) prior to testing.

1. Bring the pouch or canister to room temperature before opening it. Remove the test dipstick from the sealed pouch or closed canister and use it within one hour.

2. With the arrow pointing toward the urine specimen, immerse the test dipstick vertically in the urine specimen in such a way that urine does not cross MAX line on the test dipstick for 10-15 seconds. See the illustration below.
3. Place the test dipstick on a non-absorbent flat surface, start the timer and wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10 minutes.

QUALITY CONTROL

A procedural control is included in the test. A colored line appearing in the control line region (C) is considered an internal procedural control. It confirms sufficient specimen volume, adequate membrane wicking and correct procedural technique.

Control standards are not supplied with this kit; however, it is recommended that positive and negative controls be tested as good laboratory testing practice to confirm the test procedure and to verify proper test performance.

Urine Assay
The urine specimen must be collected in a clean and dry container. Urine collected at any time of the day may be used. Urine specimens exhibiting visible particles should be centrifuged, filtered, or allowed to settle to obtain a clear specimen for testing.

Specimen Storage
Urine specimens may be stored at 2-8°C for up to 48 hours prior to testing. For prolonged storage, specimens may be frozen and stored below -20°C. Frozen specimens should be thawed and mixed before testing.