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Cotinine Rapid Diagnostic Dipstick,Cassette,PaneTest Kits , Nicotine Metabolite Qualitative Detection With CE certified

Basic Information
Place of Origin: CHINA
Brand Name: AllTest
Certification: CE
Model Number: DCT-101、DCT-102、DCT-114
Minimum Order Quantity: 500
Packaging Details: 50T/Kit,40T/kit
Supply Ability: 100 Million a year
Format: Dipstick,Cassette,Panel Specimen: Urine
Kit Size: 50T/Kit,40T/kit Cut-Off: 10 Ng/mL, 50 Ng/mL,100 Ng/mL,200 Ng/mL,500 Ng/mL,
Storage: 2-30℃ Shelf Time: 24 Months
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A rapid test for the qualitative detection of Cotinine (nicotine metabolite) CE certified

 

 

Applications: 

 

The COT Rapid Test  (Urine) is a rapid chromatographic immunoassay for the detection of Cotinine in human urine at a cut-off concentration of 200 ng/mL. This test will detect other related compounds, please refer to the Analytical Specificity table in this package insert.

This assay provides only a preliminary analytical test result. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography and mass spectrometry (GC/MS) is the preferred confirmatory method. Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are used

 

 

Description: 

 

Cotinine is the first-stage metabolite of nicotine, a toxic alkaloid that produces stimulation of the autonomic ganglia and central nervous system when in humans. Nicotine is a drug to which virtually every member of a tobacco-smoking society is exposed whether through direct contact or second-hand inhalation. In addition to tobacco, nicotine is also commercially available as the active ingredient in smoking replacement therapies such as nicotine gum, transdermal patches and nasal sprays.

In a 24-hour urine, approximately 5% of a nicotine dose is excreted as unchanged drug with 10% as cotinine and 35% as hydroxycotinine; the concentrations of other metabolites are believed to account for less than 5%.1 While cotinine is thought to be an inactive metabolite, it’s elimination profile is more stable than that of nicotine which is largely urine pH dependent. As a result, cotinine is considered a good biological marker for determining nicotine use. The plasma half-life of nicotine is approximately 60 minutes following inhalation or parenteral administration.2 Nicotine and cotinine are rapidly eliminated by the kidney; the window of detection for cotinine in urine at a cutoff level of 200 ng/mL is expected to be up to 2-3 days after nicotine use.

The COT Rapid Test Cassette (Urine) is a rapid urine screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of Cotinine in urine. The COT Rapid Test Cassette (Urine) yields a positive result when the Cotinine in urine exceeds 200 ng/mL.

 

 

 

How to use? 

 

Allow the test, urine specimen, and/or controls to reach room temperature (15-30°C) prior to testing.
1. Bring the pouch to room temperature before opening it. Remove the test cassette from the sealed pouch and use it within one hour.
2. Place the test cassette on a clean and level surface. Hold the dropper vertically and transfer 3 full drops of urine (approx. 120μL) to the specimen well (S) of the test cassette, and then start the timer. Avoid trapping air bubbles in the specimen well (S). See the illustration below.
3. Wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10minutes.

Cotinine Rapid Diagnostic Dipstick,Cassette,PaneTest Kits , Nicotine Metabolite Qualitative Detection With  CE certified 0

【DIRECTIONS FOR PANEL USE】
Allow the test, urine specimen, and/or controls to reach room temperature (15-30ºC) prior to testing.
1. Bring the pouch to room temperature before opening it. Remove the test panel from the sealed pouch and use it within one hour.
2. Remove the cap.
3. With the arrow pointing toward the urine specimen, immerse the test panel vertically in the urine specimen for at least 10 to 15 seconds. Immerse the strip to at least the level of the wavy lines, but not above the arrow on the test panel.
4. Replace the cap and place the test panel on a non-absorbent flat surface.
5. Start the timer and wait for the colored line(s) to appear.
6. The result should be read at 5 minutes. Do not interpret the result after 10 minutes.

Cotinine Rapid Diagnostic Dipstick,Cassette,PaneTest Kits , Nicotine Metabolite Qualitative Detection With  CE certified 1

【DIRECTIONS FOR DIPSTICK USE】
Allow the test, urine specimen, and/or controls to reach room temperature (15-30ºC) prior to
testing.
1. Bring the pouch to room temperature before opening it. Remove the test dipstick from the sealed pouch and use it within one hour.
2. With arrows pointing toward the urine specimen, immerse the test dipstick vertically in the urine specimen for at least 10-15 seconds. Do not pass the maximum line (MAX) on the Test Dipstick when immersing the strip. See the illustration below.
3. Place the test dipstick on a non-absorbent flat surface, start the timer and wait for the colored line(s) to appear. Read results at 5 minutes. Do not interpret the result after 10 minutes.

Cotinine Rapid Diagnostic Dipstick,Cassette,PaneTest Kits , Nicotine Metabolite Qualitative Detection With  CE certified 2

 

INTERPRETATION OF RESULTS

 

(Please refer to the illustration above)

NEGATIVE:* Two lines appear. One colored line should be in the control line region (C), and another apparent colored line should be in the test line region (T). This negative result indicates that the Cotinine concentration is below the detectable level .

*NOTE: The shade of color in the test line region (T) may vary, but it should be considered negative whenever there is even a faint colored line.

POSITIVE: One colored line appears in the control line region (C). No line appears in the test line region (T). This positive result indicates that the Cotinine concentration exceeds the detectable level .

INVALID: Control line fails to appear. Insufficient specimen volume or incorrect procedural techniques are the most likely reasons for control line failure. Review the procedure and repeat the test using a new test. If the problem persists, discontinue using the lot immediately and contact your local distributor.

Cat. No. Product Description Specimen Format Kit Size Cut-Off Status
DCT-102 Cotinine (COT) Rapid Test Cassette Urine Cassette 40 T 10 ng/mL, 50 ng/mL,
100 ng/mL, 200 ng/mL*, 500 ng/mL
CE
DCT-114 Cotinine (COT) Rapid Test Panel Urine Panel 40 T CE
DCT-101 Cotinine (COT) Rapid Test Dipstick Urine Dipstick 50 T CE
 
   

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