QUESTIONS & ANSWERS
1. How can I know my test is working well?
If your test is working well, you will see a line in the control line area(C) on the test cassette. If there is no line in the control line area, your test did not work and the test result is invalid.
2. When is the best time to run the test?
Test can be done at any time of the day.
3. How soon can I read my results?
You can read your results at 10 minutes after sample and buffer adding, do not read result after 20 minutes.
4. Can the result be wrong? Are there any factors that can affect the test result?
The results will only give accurate results as far as the fresh fingerstick whole blood used and followed the instructions carefully. Nevertheless, the result can be incorrect. Non-SARS-CoV-2 coronavirus strains or other interference factors may cause a preliminary Positive Result.
5. How to read the test if the color and the intensity of the lines are different?
The color and intensity of the lines have no importance for result interpretation. The test should be considered as Positive whatever the color intensity of the test line (T) is.
6. What should I do if the test result is positive but I was not vaccinated?
If your test result is positive but you were not vaccinated, you should isolate yourself and contact with your local healthcare provider to perform PCR test in case of COVID-19.
7. What should I do if the test result is negative but I was vaccinated?
If you were vaccinated and the test result is negative, it may because the antibody level is below the detection level or no SARS-CoV-2 S-RBD IgG antibody detected; it is recommended to run a new test several days later. If the test result is still negative, contact with your healthcare provider.
SUMMARY
Coronaviruses infect many species of animals including humans, causing acute and chronic diseases.1 The novel coronaviruses belong to the β genus. COVID-19 is an acute respiratory infectious disease. People are generally susceptible. Currently, the patients infected by the novel coronavirus are the main source of infection; asymptomatic infected people can also be an infectious source.
Based on the current epidemiological investigation, the incubation period is 1 to 14 days, mostly 3 to 7 days. The main manifestations include fever, fatigue and dry cough. Nasal congestion, runny nose, sore throat, myalgia and diarrhea are found in a few cases. All coronaviruses share similarities in the organization and expression of their genome, in which 16 nonstructural proteins (nsp1 through nsp16), encoded by open reading frame (ORF) 1a/b at the 5’ end, are followed by the structural proteins spike (S), envelope (E), membrane (M), and nucleocapsid (N), which are encoded by other
ORFs at the 3’ end.2 The virus gains entry to the host cell through binding of the S protein receptor-binding domain (RBD) to the angiotensin-converting enzyme 2 (ACE2) receptor on target cells, particularly respiratory epithelial cells of the host. Upon infection with SARS-CoV-2, the host usually mounts an immune response against the virus.
